2-Hydroxy Acids in Plant Metabolism

Occurrence of 2-hydroxy Fatty Acids in Animal Tissues.

Metabolism of /V-Hydroxy-2-acetylaminofluorene and A/-Hydroxy-2- aminofluorene by Guinea Pig Liver Microsomes1

The guinea pig is resistant to the hepatocarcinogenic effects of 2-acetylaminofluorene and 2-aminofluorene. This resist ance, however, is not due to the lack of a A/-hydroxylating enzyme in the liver which catalyzes the first and rate-limiting step to the activation of these chemicals to proximal carcino gens. It is shown that guinea pig liver microsomes can A/-hydroxylate both of these compoun...

Ethanolamine Metabolism in Plant Tissues" 2

Summarv. Ethanolamine is readily metabolized by oat, pea, wheat, apple and carrot tissue preparations. Ethanolamine-1,2 14C was incorporated into the lipid fraction, and 14C activity was distributed in the organic acid, sugar, acid volatile, carbon dioxide and insoluble residule fractions. The distribution varied with the particular tissue. Incorporation into the lipid fraction occurred in tiss...

Benzoyl-CoA pathway-mediated metabolism of meta-hydroxy-aromatic acids in Rhodopseudomonas palustris

Metabolism of hydroxy fatty acids in dogs with steatorrhea secondary to experimentally produced intestinal blind loops.

Several aspects of the metabolism of hydroxy fatty acids were studied in dogs with steatorrhea resulting from an experimentally produced jejunal blind loop. In these animals hydroxy acids were present in the stool in amounts far above normal. These acids disappeared from the feces during tetracycline administration and after exclusion of the blind loop-both procedures that corrected the steator...